Our team has pioneered an understanding of the utilization patterns, risks, and benefits of commonly used classes of medications in the hospital setting.

These medications include:

  • Acid-suppressive medications

  • Opioids

  • Anti-psychotics

  • Sedative-hypnotics

  • Diabetes medications

  • Anti-hypertensives.

Hospital Prescribing

Publications from our team:

Wilson LM, Herzig SJ, Marcantonio ER, Steinman MA, Schonberg MA, Wang BX, Hileman-Kaplan E, Anderson TS. Management of Diabetes and Hyperglycemia in the Hospital: A Systematic Review of Clinical Practice Guidelines. Diabetes Care. 2025 Apr 1;48(4):655-664. doi: 10.2337/dc24-2510. PMID: 40117466.

Wilson LM, Abebe KZ, Anderson TS. How Should Elevated Blood Pressure Be Managed in Hospital? NEJM Evid. 2024 Dec;3(12):EVIDtt2400202. doi: 10.1056/EVIDtt2400202. Epub 2024 Nov 26. PMID: 39589191.

Bress AP, Anderson TS, Flack JM., Ghazi L, Hall ME, Laffer CL, Still CH, Taler SJ, Zachrison KS, & Chang TI. The management of elevated blood pressure in the acute care setting: A scientific statement from the American Heart Association. Hypertension. Published online May 28 2024. doi.org/10.1161/hyp.0000000000000238

Spetko N, Wang BX, Herzig SJ, Anderson TS. Prevalence and Management of Medication Interactions with Nirmatrelvir-Ritonavir at a Large Urban Academic Medical Center: An Observational Study. J GEN INTERN MED (2024). https://doi.org/10.1007/s11606-024-08750-6

Wilson LM, Herzig SJ, Steinman MA, Schonberg MA, Cluett JL, Marcantonio ER, Anderson TS. Management of Inpatient Elevated Blood Pressures: A Systematic Review of Clinical Practice Guidelines. Ann Intern Med. [Epub 2 April 2024]. doi:10.7326/M23-3251

Bernstein EY, Baggett TP, Trivedi S, Herzig SJ, Anderson TS. Outcomes After Initiation of Medications for Alcohol Use Disorder at Hospital Discharge. JAMA Netw Open. 2024;7(3):e243387. doi:10.1001/jamanetworkopen.2024.3387

Kasanagottu K, Anderson TS, Trivedi S, Ngo LH, Schnipper JL, McCarthy EP, Herzig SJ. Racial and Ethnic Disparities in Opioid Prescribing on Hospital Discharge Among Older Adults: A National Retrospective Cohort Study. J GEN INTERN MED (2024). https://doi.org/10.1007/s11606-024-08687-w

Rachoin, J-S, Cerceo, E, Anderson, TS. Things We Do For No Reason™: Intensifying antihypertensive medications for hospitalized patients at the time of discharge. J Hosp Med. 2023; 1-4.

Bernstein EY, Baggett TP, Trivedi S, Herzig SJ, Anderson TS. Pharmacologic Treatment Initiation Among Medicare Beneficiaries Hospitalized With Alcohol Use Disorder. Ann Intern Med. [Epub 27 June 2023]

Anderson TS, Herzig SJ, Jing B, et al. Clinical Outcomes of Intensive Inpatient Blood Pressure Management in Hospitalized Older Adults. JAMA Intern Med. Published online May 30, 2023. doi:10.1001/jamainternmed.2023.1667

Deshpande BR, McCarthy EP, Jung Y, Anderson TS, Herzig SJ. Initiation of Long-Acting Opioids Following Hospital Discharge Among Medicare Beneficiaries. J Hosp Med. 2021 12; 16(12):724-726. PMID: 34797996; PMCID: PMC8626058.

Anderson TS, Lee AK, Jing B, Lee S, Herzig SJ, Boscardin WJ, Fung K, Rizzo A, Steinman MA. Intensification of Diabetes Medications at Hospital Discharge and Clinical Outcomes in Older Adults in the Veterans Administration Health System. JAMA Netw Open. 2021 10 01; 4(10):e2128998.

Anderson TS, Jing B, Fung K, Steinman MA. Older Adults' Persistence to Antihypertensives Prescribed at Hospital Discharge: a Retrospective Cohort Study. J Gen Intern Med. 2021 12; 36(12):3900-3902.

Herzig SJ, Rothberg MB, Moss CR, Maddaleni G, Bertisch SM, Wong J, Zhou W, Ngo L, Anderson TS, Gurwitz JH, Marcantonio ER. Risk of in-hospital falls among medications commonly used for insomnia in hospitalized patients. Sleep. 2021 Sep 13;44(9):zsab064. doi: 10.1093/sleep/zsab064. PMID: 33710329; PMCID: PMC8436133.

Anderson TS, Lee S, Jing B, Fung K, Ngo S, Silvestrini M, Steinman MA. Prevalence of Diabetes Medication Intensifications in Older Adults Discharged From US Veterans Health Administration Hospitals. JAMA Netw Open. 2020 03 02; 3(3):e201511

Anderson TS, Jing B, Auerbach A, Wray CM, Lee S, Boscardin WJ, Fung K, Ngo S, Silvestrini M, Steinman MA. Clinical Outcomes After Intensifying Antihypertensive Medication Regimens Among Older Adults at Hospital Discharge. JAMA Intern Med. 2019 Nov 01; 179(11):1528-1536.

Anderson TS, Wray CM, Jing B, Fung K, Ngo S, Xu E, Shi Y, Steinman MA. Intensification of older adults' outpatient blood pressure treatment at hospital discharge: national retrospective cohort study. BMJ. 2018 09 12; 362:k350

Ronan MV, Herzig SJ. Hospitalizations Related To Opioid Abuse/Dependence And Associated Serious Infections Increased Sharply, 2002-12. Health Aff (Millwood). 2016 May 1;35(5):832-7. doi: 10.1377/hlthaff.2015.1424. PMID: 27140989; PMCID: PMC5240777.

Herzig SJ, Rothberg MB, Guess JR, Stevens JP, Marshall J, Gurwitz JH, Marcantonio ER. Antipsychotic Use in Hospitalized Adults: Rates, Indications, and Predictors. J Am Geriatr Soc. 2016 Feb;64(2):299-305. doi: 10.1111/jgs.13943. PMID: 26889839; PMCID: PMC4762184.

Marshall J, Herzig SJ, Howell MD, Le SH, Mathew C, Kats JS, Stevens JP. Antipsychotic utilization in the intensive care unit and in transitions of care. J Crit Care. 2016 Jun;33:119-24. doi: 10.1016/j.jcrc.2015.12.017. Epub 2015 Dec 30. PMID: 26818629; PMCID: PMC4842336.

Herzig SJ, Rothberg MB, Cheung M, Ngo LH, Marcantonio ER. Opioid utilization and opioid-related adverse events in nonsurgical patients in US hospitals. J Hosp Med. 2014 Feb;9(2):73-81. doi: 10.1002/jhm.2102. Epub 2013 Nov 13. PMID: 24227700; PMCID: PMC3976956.

Herzig SJ, Vaughn BP, Howell MD, Ngo LH, Marcantonio ER. Acid-suppressive medication use and the risk for nosocomial gastrointestinal tract bleeding. Arch Intern Med. 2011 Jun 13;171(11):991-7. doi: 10.1001/archinternmed.2011.14. Epub 2011 Feb 14. PMID: 21321285; PMCID: PMC3142477.

Herzig SJ, Howell MD, Ngo LH, Marcantonio ER. Acid-suppressive medication use and the risk for hospital-acquired pneumonia. JAMA. 2009 May 27;301(20):2120-8. doi: 10.1001/jama.2009.722. PMID: 19470989.